Upstream Scientist - Technical Services/Manufacturing Sciences Laboratory

We’re looking for people who are determined to make life better for people around the world.At Lilly, we serve an extraordinary purpose. We make a difference for people around the globe by discovering, developing and delivering medicines that help them live longer, healthier, more active lives. Not only do we deliver breakthrough medications, but you also can count on us to develop creative solutions to support communities through philanthropy and volunteerism.Owing to the continuous growth of our Monoclonal pipeline of products, Eli Lilly & Company has invested in a new facility in Ireland, Lilly Limerick. To support this exciting new investment and meet the requirements of a safe and successful start-up, we are eager for talented individuals to join our team(s) and contribute to establishing Lilly Limerick as a reliable supplier of our innovative medicines and our goal of making a difference to people’s lives.If you are looking for a challenging, rewarding career and feel you meet the requirements listed below we would love to consider you for a role at Lilly, Limerick.Upstream Scientist - Technical Services/Manufacturing Sciences LaboratoryThe TS/MS Upstream Scientist will provide direct technical support for the design, startup and execution of the TS/MS laboratory. This role will provide technical expertise for the laboratory startup activities including facility design, instrument procurement and qualification in support upstream operations. The successful applicant will have technical expertise in laboratory scale models for upstream operations and demonstrate strong data-driven decision-making and problem-solving capabilities. They will work to continuously improve process efficiency by implementing new technologies and process improvements in addition to investigation support. This role will incorporate the use of data analytics and process analytical technology to support the next generation bioprocessing facility in laboratory scale models to drive process development.Key ResponsibilitiesHave an in-depth knowledge of the science of biotech manufacturing and associated laboratory models and analytical tests, supporting upstream processing.Expertise in laboratory scale equipment operation and trouble shooting.Understand molecule-specific control strategy and basis of specifications and critical quality attributes.Work with the network and development organizations to ensure a well-understood, robust and fit-for-purpose laboratory models are developed and transferred. This will include those specific to the NGB processing including implementation of process analytical technologies in support of multivariate analyses and process modelling.Experience with the application of Raman spectroscopy integration into mammalian cell culture bioreactorsLeading laboratory investigations in support of production operations.Support the design and start-up of the laboratory including equipment configuration and purchase, development of the laboratory data management strategy, establishment of laboratory protocolsSupport a laboratory startup plan in alignment with the health, safety and environmental team to ensure safe startup and operation.Create and review documents including laboratory SOPs, material specifications, protocols, and work instructionsEstablish partnerships to enable cross functional work with the quality control laboratory and other Lilly sites to ensure facility startup objectives are met.Understand basic statistical methodologies and statistically based experimental design.Identify process improvements and participate in implementation of Lean manufacturing initiativesContribute to the authorship and review of regulatory submissions and responses to regulatory agenciesBasic Requirements:PhD degree based in biology, chemistry, biochemistry or similar discipline.Experience (>3 yrs) working in pharmaceutical laboratory and GMP manufacturing environments.Additional Requirements:Demonstrated technical capability with high productivityProven track record of curiosity with learning agilitySelf-starter with high initiative and data-driven approach to problem-solvingDemonstrated strong interpersonal skillsDemonstrated strong verbal and written communication skillsDemonstrated adaptability and flexibility to working in different environments, teams etc.Demonstrated ability to participate in and facilitate decision-makingProficient in EnglishWork Environment:These are 8-hour day roles. As a manufacturing support function, the need for occasional evening or weekend support can arise.Although expected to be minimal, occasional travel is possible including to other Lilly sites both in- and outside of Ireland.Lilly does not discriminate on the basis of age, race, color, religion, gender, sexual orientation, gender identity, gender expression, national origin, protected veteran status, disability or any other legally protected status.#WeAreLilly